詹姆斯一. Peliska博士

Dean of the 艺术学院 and 科学
Professor of Biochemistry and Chemistry
Fellow in Catholic Studies

艺术学院 & 科学

关于我的

I started my academic career as a professor at the University of Michigan School of Medicine. 在密歇根, I developed my ongoing research program in HIV-1 replication, and I was involved in the initiation of their undergraduate Biochemistry program. For the last 20 years, I have been a leader in Catholic higher education as a professor, as a department chair, and in my current role as Dean of the 艺术学院 and 科学, overseeing these programs at the University of Mary. I maintain an active student-engaged research program in HIV-1 drug discovery and work with colleagues in the development of modern and relevant courses in the sciences.

Why I’m At Mary

I am at the University of Mary because it is one of the few universities I have encountered where one can engage with students in the rigorous pursuit of scientific inquiry while remaining fully integrated into a faithful and authentically Catholic university culture. I moved to Mary five years ago because I believe that this university is making a real difference in the development of servant leaders, and is quickly becoming a leader in Catholic higher education. It is exciting to be a part of this great project.

专业知识

My scientific expertise is in the areas of chemistry and biochemistry. From an administrative perspective, I have extensive experience in program and curriculum development.

Viranga L.M., A. Tillekeratne,. Sherette J.A. Fulmer L. Hupe D. Hupe,年代. Gabbara J.A. Peliska和R.A. 哈德逊. (2002). “ChemInform Abstract: Differential Inhibition of Polymerase and Strand-Transfer Activities of HIV-1 Reverse Transcriptase,“CHEMINFORM. 33(24).

Tillekeratne L.M., A. Sherette J.A. Fulmer L. Hupe D. Hupe,年代. Gabbara J.A. Peliska和R.A. 哈德逊. (2002). “Differential Inhibition of Polymerase and Strand-Transfer Activities of HIV-1 Reverse Transcriptase,” Bioorg Med Chem Lett. 12(4):525-8.

江,P., J.A. Peliska和A.J. Ninfa. (2001). “Asymmetry in the Autophosphorylation of the Two Component Regulatory System Transmitter Protein Nitrogen Regulator II of Escherichia Coli.,“生物化学. 39:5057-5065.

戴维斯W., J. Tomsho,年代. Nikam E.M. 做饭,维. Somand and J.A. Peliska. (2000). “Inhibition of HIV-1 Reverse Transcriptase Catalyzed DNA Strand Transfer Reactions by the 4-Chlorophenylhydrazone of Mesoxalic Acid,“生物化学. 46:14279-14291.

Ninfa,.J., P. 江,M.R. Atkinson, and J.A. Peliska. “Integration of Antagonistic Signals in the Regulation of Bacterial Nitrogen Assimilation,” Current Topics Cellular Regulation. 36:32-75.

Gabbara,年代., W. 戴维斯,我. Hupe D. 希望，和J.A. Peliska. (1999). “Inhibitors of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase,“生物化学. 38:13070-13076.

戴维斯W., S. Gabbara D. 霍普和J.A. Peliska. (1999). “Actinomycin D Inhibition of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase and Nucleocapsid Protein,“生物化学. 37:14213-14221.

江,P., J.A. Peliska和A.J. Ninfa. (1998). “The Regulation of Escherichia Coli Glutamine Synthetase Revisited: Role of 2-Ketoglutarate in the Regulation of Glutamine Synthetase Adenylylation State,“生物化学. 37:12802-12810.

江,P., J.A. Peliska和A.J. Ninfa. (1998). “Reconstitution of the Signal-Transduction Bicyclic Cascade Responsible for the Regulation of Ntr Gene Transcription in Eschericia Coli,“生物化学. 37:12795-12801.

江,P., J.A. Peliska和A.J. Ninfa. (1998). “Enzymological Characterization of the Signal-Transducing Uridylyltransferase/Uridylyl-Removing Enzyme of Escherichia Coli and its Interaction with the PII Protein,“生物化学. 37:12782-12794.

弗瑞,年代., C. 乔伊斯,米. 奥斯本,D. Klenerman J.A. Peliska和S. Balasubramanian. (1998). “Use of Fluorescence Resonance Energy Transfer to Investigate the Conformation of DNA Substrates Bound to the Klenow Fragment,“生物化学. 37:2979-2990.

Peliska J.A., S. Balasubramanian, D.P. Giedroc C. 德巴克和S.J. Benkovic. (1994). “Recombinant HIV-1 Nucleocapsid Protein Accelerates HIV-1 Reverse Transcriptase Catalyzed DNA Strand Transfer Reactions and Modulates RNase H Activity,“生物化学. 33:13817-13823.

Peliska J.A.， S.J. Benkovic. (1994). “The Fidelity of In Vitro DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase,“生物化学. 33: 3890-3895.

Peliska J.A.， S.J. Benkovic. (1992). “A Handy Enzyme for Transcription,” Current Biology. 2(10): 521-523.

Peliska J.A.， S.J. Benkovic. (1992). “Mechanism of DNA Strand Transfer Reactions Catalyzed By HIV-1 Reverse Transcriptase,” Science. 258: 1112-1118.

Peliska J.A.， M.H. 奥利里. (1991). “Sulfuryl Transfer Catalyzed by Phosphokinases,“生物化学. 30:1049-1057.

Peliska J.A.， M.H. 奥利里. (1989). “Sulfuryl Transfer Catalyzed by Pyruvate Kinase,“生物化学. 28:1604-1611.

教育

BS (Biology/Chemistry): Northland College, 1985
PhD (Chemistry): University of Wisconsin — Madison
NIH Postdoctoral Fellowship — Penn State University